• Motivation: why do we need Knowledge Portals?
• History of the Knowledge Portal platform
• A2FKP data content
ㅇ Genetic data
ㅇ Genomic data
ㅇ Curated knowledge
• Analysis methods
• Core pages of the A2FKP and navigation
• Signature tools
• Use cases: examples of the independent exercises
• The “Bring Your Own Results” platform for visualizing and sharing your research
1. Choose a gene of interest. Use the A2FKP to form a hypothesis about its role in a complex disease or trait.
2. Choose a disease of interest. Use the A2FKP to form a hypothesis about which gene at a genetically associated locus is involved in the disease.
It is not required, but could be helpful for students to prepare by:
• Familiarizing themselves with the A2FKP (a2fkp.org). Many of the tools and interfaces are explained in the Help documentation section (https://a2f.hugeamp.org/help.html)
• Reading our recent article: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(23)00079-7 The article describes the Type 2 Diabetes Knowledge Portal, but its data and architecture are analogous to those of the A2FKP.
• Reading a short article on understanding genetic association data: https://a2f.hugeamp.org/help.html?page=1036
• If students have questions before the workshop, they are welcome to contact us at help@kp4cd.org.
※ 영어로 진행되는 강좌입니다.
※ 온라인으로만 진행되는 강좌입니다.
별도 오프라인 강의장이 없으므로 개별적으로 편한 장소에서 zoom 접속하여 수강하시기 바랍니다.
| 구분 | 세션 | 시간 | 강의내용 | 강사명 | 비고 |
|---|---|---|---|---|---|
| Day 1 | Session 1 | 09:30~10:50 | Overview of the Knowledge Portal platform | Maria Costanzo and colleagues | Lecture |
| Day 1 | Session 2 | 10:50~11:00 | Break | - | - |
| Day 1 | Session 3 | 11:00~12:30 | Independent exercises | Maria Costanzo and colleagues | Practice |